6:42PM
A Dose of Medical News #1.2 - Adding Clopidogrel to Aspirin in Patient with Atrial Fibrillation
Thursday, April 2, 2009 at 6:42PM Being a Haematologist, I know the pain of having to take warfarin and its potential interaction and pantangs!Yes, Rivaroxaban and Ximelagatran maybe around the corner but while we wait, how about a good dose of antiplatelets instead of trusty old warfarin?
The ACTIVE trial investigators published their results if we add 75mg of Clopidogrel on top of Aspirin. It significantly reduces the rate of stroke by 28%, at the expense of increased risk of major bleeding by 57%. There is no reduction in the rate of myocardial infarction (heart attack). Hmmm! It may have a place in young patient.
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